Jorge Goldstein Selected Research

Shiga Toxin 2

2/2019	Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hippocampus.
12/2018	Anti-inflammatory agents reduce microglial response, demyelinating process and neuronal toxin uptake in a model of encephalopathy produced by Shiga Toxin 2.
1/2017	Dexamethasone prevents motor deficits and neurovascular damage produced by shiga toxin 2 and lipopolysaccharide in the mouse striatum.
9/2014	Retinoid levels influence enterohemorrhagic Escherichia coli infection and Shiga toxin 2 susceptibility in mice.
1/2013	Dexamethasone rescues neurovascular unit integrity from cell damage caused by systemic administration of shiga toxin 2 and lipopolysaccharide in mice motor cortex.
1/2013	A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum.

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Jorge Goldstein Research Topics

Disease

9	Hemolytic-Uremic Syndrome 02/2019 - 01/2006
7	Infections 09/2022 - 01/2013
4	Brain Diseases (Brain Disorder) 02/2019 - 09/2008
4	Colitis 09/2014 - 08/2007
2	Edema (Dropsy) 02/2019 - 08/2012
2	Diarrhea 02/2019 - 01/2017
2	Neurologic Manifestations (Neurological Manifestations) 01/2013 - 08/2012
1	Fever (Fevers) 01/2019
1	Inflammation (Inflammations) 01/2019
1	Brain Edema (Cerebral Edema) 05/2017
1	Encephalomalacia 05/2017
1	Ganglion Cysts (Ganglion) 04/2013
1	Infant Death 09/2008
1	Gliosis 09/2008
1	Brain Injuries (Brain Injury) 09/2008
1	AIDS-Related Complex (ARC) 01/2007
1	Starvation 08/2004

Drug/Important Bio-Agent (IBA)

8	Shiga Toxin (Shigella Toxin)IBA 09/2022 - 01/2006
6	Shiga Toxin 2IBA 02/2019 - 01/2013
2	LipopolysaccharidesIBA 09/2022 - 01/2019
2	Shiga Toxins (Vero Toxin)IBA 01/2018 - 10/2013
2	Proteins (Proteins, Gene)FDA Link 08/2012 - 08/2004
1	Virulence Factors (Pathogenicity Factors)IBA 09/2022
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2018
1	VaccinesIBA 09/2018
1	Clostridium perfringens epsilon-toxinIBA 05/2017
1	Vitamin A (Retinol)FDA LinkGeneric 09/2014
1	RetinoidsIBA 09/2014
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2013
1	Retinaldehyde (Retinal)IBA 04/2013
1	AdrenomedullinIBA 04/2013
1	Pharmaceutical PreparationsIBA 01/2013
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2013
1	Aquaporins (Water Channels)IBA 08/2012
1	NADP (NADPH)IBA 09/2008
1	Glial Fibrillary Acidic ProteinIBA 09/2008
1	ProlactinIBA 01/2007
1	Peptides (Polypeptides)IBA 01/2007
1	Dopamine (Intropin)FDA LinkGeneric 01/2007
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 01/2007
1	LeptinIBA 08/2004

Therapy/Procedure

1	Intravenous Administration 01/2013